Revisiting preeclampsia: a metabolic disorder of the placenta
نویسندگان
چکیده
منابع مشابه
Effect of Placenta Previa on Preeclampsia
BACKGROUND The correlation between gestational hypertension-preeclampsia (GH-PE) and placenta previa (PP) is controversial. Specifically, it is unknown whether placenta previa has any effect on the various types of preeclampsia (PE), and the role PP with concurrent placenta accreta (PA) play in the occurrence of GH-PE are not well understood. OBJECTIVE The aim of this study was to identify th...
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Preeclampsia remains a leading cause of maternal and fetal mortality, due to ineffective treatment and diagnostic strategies, compounded by the lack of clarity on the etiology of the disorder. Although several clinical and biological markers of preeclampsia have been evaluated, they have proven to be ineffective in providing a definitive diagnosis during the various stages of the disorder. Exos...
متن کاملRedefining preeclampsia using placenta-derived biomarkers.
1 Acute maternal complications include eclampsia, stroke, placen-tal abruption, disseminated intravascular coagulation, HELLP (hemolysis, elevated liver enzymes, low platelets), liver hemorrhage or rupture, pulmonary edema, adult respiratory distress syndrome, acute renal failure, and death. 2 Preeclampsia complications account for more than 50 000 maternal deaths annually. 2,3 In developing co...
متن کاملComprehensive Analysis of Preeclampsia-Associated DNA Methylation in the Placenta
BACKGROUND A small number of recent reports have suggested that altered placental DNA methylation may be associated with early onset preeclampsia. It is important that further studies be undertaken to confirm and develop these findings. We therefore undertook a systematic analysis of DNA methylation patterns in placental tissue from 24 women with preeclampsia and 24 with uncomplicated pregnancy...
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ژورنال
عنوان ژورنال: The FEBS Journal
سال: 2021
ISSN: 1742-464X,1742-4658
DOI: 10.1111/febs.15745